Introduction to Dapagliflozin 10mg and Metformin 500mg SR Extended Release Dapagliflozin 5mg and Metformin 500mg SR Extended Release combination is a medication used to manage type 2 diabetes mellitus. It is a combination of two drugs: dapagliflozin and metformin. Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that works by inhibiting SGLT2 in the kidneys, reducing glucose reabsorption, and promoting the excretion of glucose in the urine. This helps lower blood sugar levels in people with type 2 diabetes. Metformin, on the other hand, is a biguanide antidiabetic medication that works by decreasing the production of glucose in the liver, reducing intestinal glucose absorption, and increasing glucose uptake and utilization in peripheral tissues. The sustained-release formulation of metformin allows for once-daily dosing.
Indication This medication is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. This medication is also used to treat kidney disease or heart failure in people with type 2 diabetes. It helps to lower the risk of death from heart disease and reduces the need of going to a hospital to treat heart failure.
Administration The medication is typically taken orally, once daily, with a meal or as directed by a healthcare professional. Swallow the tablet or extended-release tablet whole with a full glass of water. Do not crush, break, or chew it. While taking the extended-release tablet, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.
Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Side Effects Common side effects may include urinary tract infections, genital yeast infections, increased urination, diarrhea, nausea, vomiting, headache, or dizziness, difficulty in urination.
Contraindications Acute or chronic metabolic acidosis including diabetic ketoacidosis Severe renal impairment Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy. Advise women of childbearing potential of fetal risk.

Safety Advice / Warnings Avoid alcohol and tobacco consumption while taking this medicine. Hyperglycemia (high blood sugar) may occur if you do not take enough or skip a dose of your medicine, overeat or do not follow your meal plan, have a fever or infection, or do not exercise as much as usual. High blood sugar can be very serious and must be treated right away. It is important that you learn which symptoms you have in order to treat it quickly. Talk to your doctor about the best way to treat high blood sugar. Dizziness, lightheadedness, or fainting may occur with this medicine. Drink plenty of water during exercise or in hot weather. Check with your doctor if you have severe nausea, vomiting, or diarrhea that does not stop. This may cause you to lose too much water.

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Weight 0.5 kg
Dimensions 20 × 10 × 15 cm
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